Zispin tablets contain mirtazapine, which belongs to a group of antidepressants. Mirtazapine helps neurotransmitters such as noradrenaline and serotonin, to be more effective. These two neurotransmitters affect our psychological state. When we have enough of them, we are in a good mood, but when we don’t, that’s when depression comes. Mirtazapine releases noradrenaline and serotonin from the neurons and it results in the improvement of our mood.This medicine can begin to work after two to four weeks of usage. At the beginning of usage you may not feel the changes but you have to continue using it. If your condition worsens, consult your doctor immediately. The instructions on how to use this medicine come with the medicine. It is important that you read them carefully and follow them. The tablet should be put in your mouth and it will decompose there so that it can be swallowed without water.This medicine is made for treating depression. If you feel worse while taking this medicine, if you have negative thoughts or desire to harm yourself you must talk to your doctor. This usually happens during the first few weeks of using Zispin, but it may also occur later or even after the treatment. During these first weeks you may feel restless or agitated. While using Zispin you could feel dizzy and sleepy. If this happens do not drive. Alcohol can enhance sleepiness, so it shouldn’t be consumed while taking Zispin. Therefore, abstain from taking alcohol during the treatment. Rarely Zispin can cause the drop of white blood cells. It can also cause hypoataemia, seizures and jaundice. Quitting the medicine should go slowly. It will take some time to completely stop using this medicine. If you abruptly stop the treatment, there is a danger that the unpleasant withdrawal of the symptoms will occur.This medicine should be used with attention in older and young persons, those who have tried to commit suicide, people who are bipolar and schizophrenic. Also, Zispin should be used with caution if someone has problems with kidney and liver, heart condition, hypotension, epilepsy or any kind of risk of convulsions, glaucoma. This medicine shouldn’t be used in those who used MAO inhibitors during the last two weeks and in children under the age of 18.There are some amount of side effects that may occur while using Zispin, such as sleepiness, lack of energy, swelling from accumulating fluid in the body, vertigo, headache, changes in the liver function, bad dreams, agitation and tremor. Mentioned side effects are only some of the most common side effects that can occur. For additional information, please read the leaflet that comes with the medicine or contact your doctor.