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Riluzole and its role

Riluzole is a drug which is used in the treatment of amyotrophic lateral sclerosis, disease that is also commonlyknown as Lou Gehrig's disease. Riluzole is available in the form of tablets andcan be obtained only with the prescription from a doctor. The main role of this medicine is toreduce the amounts of glutamate that affects the nerves by which muscles getthe message from the brain. Riluzole must be taken exactly as the doctorprescribed it, usually twice a day on empty stomach or one hour before or twohours after the meal.

Complications when using riluzole

It is important to tell the doctorif the patient has some other medical problems, especially the lung or liverdiseases, as well as kidney disorder and bone marrow problems. These conditionsmay be worsened by the use of riluzole. Riluzole must not be used along withsome other medications, such as sulfasalazine, tacrine and theophylline. It is also important to inform thedoctor in the case of some allergic reactions to the ingredients of thismedicine. It is advisable not to consumealcohol, caffeine or nicotine while taking riluzole.

Side effects of riluzole

Each medicine has its unwanted effects, and thus riluzole as well. The most common side effects ofriluzole are problems with eyes or blurred vision, problems with breathing,difficult moving as well as dizziness, headache, muscle tension or pain orstiffness and pain in the joints. Furthermore, nervousness, pounding in the earand slow or rapid heartbeat are also some of the frequent side effects ofriluzole.

Other adverse effects that are lesscommon are pain of bladder, cough, swelling of the face or extremities, bluishlips or skin, as well as chills, confusion, burning while urinating or bloody orcloudy urine and cold sweats. Moreover, some persons reported diarrhea,vomiting, nausea, the loss of weight and the loss of appetite as unwanted sideeffects of this medicine. In some cases fever, headache, tenderness, hypotension,sleeplessness and unconsciousness appeared. It is not unusual that difficultywhile swallowing, frequent urge to urinate, pains in muscles, jointsor lower back, and sore throat will appear. Furthermore, increased sputum, shivering,sneezing, and runny nose may also occur as side effects of riluzole.

Very rare side effects of riluzoleare mood swings, weakness, fatigue, confusion, lack of concentration, thirst,depression as well as redness, scaling, or peeling of the skin. In addition tothese very rare side effects, convulsion, swelling of the eyelids, lips, tongueor mouth and jaundice can sometimes occur.

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