What is trimethoprim?
Trimethoprim is the name for anantibiotic that has the role to fight against bacteria in the body, and thedoctors usually prescribe it in treatment of bladder infection that is inducedby some bacteria. Before using this medicine, it is very important toinform the doctor about existing medical condition. It is not recommended touse it if the patient already has or had some problems or disease of thekidneys, liver or heart. Furthermore, the person must not use trimethoprim ifhe or she is allergic to some of the ingredient of this medicine. Moreover,anemia and folic acid insufficiency must also be reported to thedoctor, because all these conditions may become worse when trimethoprim istaken.
If a woman is pregnant or if sheplans to become pregnant, it is not advisable to use trimethoprim, because thisdrug may have some negative and unwanted effects on the unborn child. The womanmust avoid using this medicine if she breastfeeds her newborn child.
Side effects of trimethoprim
Trimethoprim is a drug that hasits adverse side effects like most medicines, and they can even appear incombination or in various forms. The most common side effect oftrimethoprim is skin sensitivity to sunlight, which results in rashes,exfoliative dermatitis, Stevens-Johnson syndrome, anaphylaxis and otherconditions. In some cases, diffuse pneumonitis occurs as a side effect of thisdrug. Of dermatologic side effects, the most frequent are maculopapular,morbilliform and pruritic rashes, though phototoxic reactions are also reportedas the adverse effects when trimethoprim is taken. Hives and itching are alsovery frequent side effects of trimethoprim.
Hyperkalemia and hyponatremia aretwo common metabolic side effects, while cholestatic jaundice and elevations ofserum transaminases and bilirubin are two common hepatic side effects of thismedicine. Gastrointestinal adverse effects that may appear when this drugis consumed are stomach upset, nausea and vomiting, as well as mild abdominaldistress, glossitis, and pseudomembranous colitis. Aseptic meningitis is anervous system side effect of trimethoprim, whereas of hematologic sideeffects, the most usual are leukopenia, megaloblastic anemia, neutropenia, andthrombocytopenia.
Some respiratory system sideeffects may occur, such as difficulty while breathing or pain in the chest. Themost typical renal adverse effect of trimethoprim severe diarrhea, and bloody, blackor tarry stools. Other very common side effects of this drug are swellingof the face, chills, fever, sore throat, jaundice and pain in muscles or jointsas well as unexplained weakness and fatigue. Some persons that consumed thismedicine reported irregular heartbeats, seizures, painful or stiff neck,vaginal irritation or discharge and decreased urination.