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Pyrazinamide

Pyrazinamide is the medicine which is antibiotic and which isused for the treatment of tuberculosis. The drug is largely bacteriostatic, butcan be bactericidal on actively replicating tuberculosis bacteria.

Side effects of Pyrazinamide

Like most drugs, pyrazinamide may have undesirableeffects. These side effects may appear or not, and their influence depends andvary from person to person. It is always important to consult the doctor beforestarting to use any drugs including pyrazinamide. The doctor must be informed ifthe person uses some other drugs in order to prescribe the proper dose of thisdrug, because its effectiveness may be increased or reduced when it is consumedin the combination whit some other remedies.

It is crucial to inform the doctor if suffering fromliver or heart disease, diabetes mellitus, if the patient has some problemswith gout, or is allergic to pyrazinamide. It is also recommended not to use it while pregnant orwhile breastfeeding the baby because the effects of thisdrug on the new-born child are not yet known.

The most frequent of all adverse effects of pyrazinamideis artaglaria, the medical term for the pain in the joints. Thispain is never so strong or unendurable, so the patients usually continues to takethis drug as a medicine to treat their illness. Pain in the joints is sometimesstressful but never harmful for the patient. Of cardiovascular side effects, acute hypertensionmay appear. Furthermore, nausea and vomiting, as well as jaundiceand malaise are hepatic side effects that can appear when the person consumespyrazinamide. Moreover, granulomatous hepatitis is not quite common but may also occur. Fever,chills, and great fatigue are some of the effects of this medicine.

One of the most serious side effects of pyrazinamideis hepatotoxicity. This adverse effect is usually differently experienced and depends on the doses of this medicine which is taken in.It is quite common that the doctor will give the patient a test to check thedosage. Some allergic skin reactions, such as skin rash oritching may occur, as well as urticaria, pruritus, skin pigmentation,desquamation, and photosensitivity.

Anorexia and anemia are quite frequentadverse side effects of this drug. In addition to the side effects ofpyrazinamide that have been mentioned so far, disuria, hyperuricemia, as well as interstitial nephritis are renaladverse effects which are reported by the consumers of this medicine. It is very important to visit the doctor if some ofthese side effects appear.

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