A certain number of clinical trials has shown that the herb known by the name of ginkgo biloba may be very effective when it comes to the treatment of the medical condition known as tinnitus.
All the randomized controlled trials of gingko biloba for tinnitus were identified using the computerized literature searches. Different database used in the research also included Embase, Medline and the Cochrane Library. The keywords used in the search included hearing disorders, tinnitus, gingko, gingko biloba and ginkgo. All the different manufacturers of various gingko biloba preparations were also asked to contribute their unpublished and published material concerning the subject. Language of various publications was not considered as a restriction. All trials were performed on patients who suffer from tinnitus. The patients treated with gingko biloba were then compared with those who were treated with an active medication or a placebo. Those whose primary complaint was not tinnitus were also rejected.
Meyer headed a team which dealt with two parallel groups of 103 and 17 tinnitus patients. Those who suffered from any acute diseases and those who had surgery or infections were not included in the study. The patients were treated either with gingko biloba or a placebo. The severity score of the symptoms of the tinnitus was used for the evaluation of the therapeutic success. Those who were treated with gingko biloba experienced significant improvement. Another study by the same author which included 259 patients suffering from tinnitus has also shown that all patients treated with gingko biloba soon experienced significant improvement, which was not the case with the others who were treated with nicergoline or almitrine-raubasine. Holger from Sweden performed a slightly different study which is characterized by certain unusal features. The end result of the study is that the number of patients who prefer the gingko biloba treatment over the treatment with placebo is exactly the same as the number of patients who prefer the placebo treatment over the treatment with gingko biloba.
Morgenstern and Bierman included 99 patients in their study, and all of them suffered from chronic tinnitus. The primary endpoint of the study was to determine the loudness of the tinnitus in an audiometrical manner. The loudness was always reduced in the patients who were treated with the gingko biloba medications. Juretzek also conducted a study which involved patients who suffer from chronic tinnitus. The study has shown that the average loudness reduction is somewhere around 8.5 dB.