What is 5-Hydroxytryptophan?
5-Hydroxytryptophan is sometimes also referred to asoxitriptan, but in most cases it is abbreviated to 5-HTP. It is actually anaturally occurring type of amino acid. It is the metabolic intermediate in thechemical precursor for the process of biosynthesis of melatonin and serotoninfrom tryptophan. For those who do not know, melatonin and serotonin are certaintypes of very important neurotransmitters. 5-HTP can be purchased in the formof dietary supplements and as such it is widely used for numerous medicinalpurposes. Some use it is a sleep aid, some others use it for the suppression ofappetite while there are also a large number of people around the world who useit for the alleviation and treatment of depression. It can be purchased undernumerous different trade names, depending on the market and the region of theworld. There were even certain scientific studies which have shown that 5-HTPcan be of some help to a certain extent to all those who suffer from thesymptoms of depression. Even though it can be purchased in the form of asupplement, 5-HTP may also be obtained from certain types of dietary sources. Thebest dietary sources of 5-HTP include pumpkin, potatoes, milk, turkey andvarious types of green leafy vegetables. 5-HTP in its supplemental form iscommonly sold over the counter in most well equipped pharmacies without theneed for a doctor’s prescription. When purchased in such supplemental form, the5-HTP commonly comes in the form of vegetarian or gelatin capsules of 50milligram or 100 milligram dosage. These capsules are commonly sourced from theseeds of the plant botanically referred to as griffonia simplicifolia.According to certain scientific studies, 5-HTP may come in very handy for thosewho suffer from primary fibromyalgia syndrome and depression. Oral usage of5-HTP is very efficient in alleviating the symptoms of fibromyalgia whichcommonly include sleeplessness, morning stiffness and quite severe painfulsensations. Other medical conditions which can be treated successfully by using5-HTP in its supplemental form include anxiety, insomnia, binge eating associatedwith obesity and Friedrich’s ataxia. There were a certain number of cases oftension headaches which saw some improvement after being treated with 5-HTP. Thiscannot be said for those who suffer from chronic types of headaches, it wereonly the acute ones which were involved in the aforementioned improvement ofthe condition. Some sources claim that it may be helpful to a certain extent inthe prevention and treatment of several other severe and less severe medicalconditions such as premenstrual syndrome, attention deficit hyperactivitydisorder, premenstrual dysphoric disorder, obesity, anxiety disorders,Alzheimer’s disease, numerous different types of sleep disorders and manyothers. Unfortunately there are not yet some scientific studies performed whichwould confirm the efficacy of 5-HTP in such medical situations.
Side effects from 5-Hydroxytryptophan
As is the case with most other types of prescriptionmedications, non prescription medications, herbal remedies, supplements,solutions and all other substances commonly used for the prevention andtreatment of numerous sorts of ailments and medical conditions,5-Hydroxytryptophan may sometimes be associated with certain unwanted sideeffects. They do not necessarily occur in all persons who use the supplement,and even when they do they may manifest differently from person to person interms of severity. 5-HTP may sometimes lead to the development of hypertensionif not administered in combination with some sort of peripheral aromaticL-amino acid decarboxylase inhibitor. In most cases the commonly usedinhibitors include benserazide and carbidopa. An overdose of 5-HTP may beparticularly dangerous as it can be associated with cardiac fibrosis, heartdisease, heart valve damage, acute serotonin syndrome, vomiting, nausea andeosinophilia-myalgia syndrome. This last condition is a very serious one whichis characterized by certain symptoms such as blood abnormalities, myalgia andextreme muscle tenderness. Pregnant women and women who plan to become pregnantshould steer clear of this supplement because it may have some unwanted harmfuleffects on the unborn child. The same goes for breastfeeding women, because5-HTP may pass into the mother’s milk and cause the same harmful effects.People who suffer from the Down syndrome should avoid using this type ofsupplement because it may lead to the occurrence of seizures. Another bigproblem with 5-HTP is that it may interact with certain other medications andcause further medical problems. It mat interact with different types ofmedications commonly used for the treatment of depression and trigger some sideeffects such as anxiety, shivering, heart problems and several others.Carbidopa is another medicament which interact with 5-HTP and when it does ittriggers aggressiveness, anxiety and rapid speech, among others. Dextromethorphaninteracts with 5-HTP and causes anxiety, shivering and heart problems.Meperidine triggers the same side effects when interacting with5-HTP.Pentazocine and tramadol may also interact with this supplement.