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Paludrine is one of the medicines which are used in the prevention of malaria, or, more precisely, in the prevention of some types of this disease. The reason why it cannot be used in all the cases of malaria is the fact that there are several types of this disease, depending on the part of the world in which malaria exists, and not all of them are equally treated, since the medicine is not equally effective with all the types.
A person who has plans to travel to the area in which it is possible to be infected, should start taking Paludrine a week before the trip. Paludrine should be used all the time while in that area, and its usage should be continued for four weeks after the trip.
Just like it is the case with every other medicine, this one is not intended for everybody. It is important not to use it without a prescription, because medical history of the individual is very important before determining whether or not he or she should use it. For example, older people are not advised to use it, as well as people with kidney problems or with allergic reactions to some of its ingredients. Pregnant and breast-feeding women should use this medicine only if their doctor finds it necessary, otherwise, they should avoid it.
Speaking of the side effects of Paludrine, in most of the cases, they might appear only as some kind of mild inconvenience. The most common side effects are diarrhea, constipation, vomiting, pain in the stomach, loss of appetite and mouth ulcers. Headache, dizziness and insomnia are also possible. The symptoms to which everyone who uses this medicine should pay a bit more attention are allergic reactions, inflammation of the mouth, skin problems and hair loss, urticaria, vasculitis and problems with blood. These symptoms can be more than just an inconvenience, so if they persist, a person should address to the doctor, and ask for the advice. Even though there are no dangerous or potentially life-threatening consequences of Paludrine, this medicine should not be used in the combination with certain antibiotics, or some gastrointestinal drugs. Some medicines lower the effectiveness of Paludrine, which means that the dosage should be increased in that case, but thus the possibility for some of the side effects or other complications will be increased as well. Such complications include angioedema, shock, difficult breathing and anaphylaxis and even hallucinations and seizures.
All of this implies that even though this medicine is available without a prescription, it should not be used without previous medical consultation.

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