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Introduction

Tylenol is a medication that is commonly used to relievefever and pain and it is very efficient in the treatment of arthritis,headache, cold, toothache, muscle ache, backache and fever. It can be also usedfor the treatment of certain other conditions. Tylenol should never be usedmore than recommended because a Tylenol overdose could cause serious damage tothe liver. Those who ingest moderate amounts of alcohol on a regular basis shouldconsult the doctor before taking Tylenol. It should never be mixed with anycough, allergy, pain or cold medications that contain acetaminophen.

Side Effects

Hepatic side effects of Tylenol include hepatotoxicity andsevere hepatitis which may sometimes even be fatal if it occurs in patients whoare alcoholics. Even the modest doses of Tylenol can sometimes triggerhepatotoxicity in alcoholic patients. Rare cases may also includeagranulocytosis, plasmacytosis and even a leukemoid reaction. Gatrointestinal side effects of Tylenolinclude cholestasis and acute biliary pain, while acute pancreatitis may occurin extremely rare cases.

Renal side effects are the rarest of all side effectscaused by Tylenol and when they occur they commonly include interstitialnephritis, acute tubular necrosis and acute renal failure. The renal side effectsare usually caused by chronic abuse hepatotoxicity or an overdose. Some rarecases may also include renal cell carcinoma while the occurrence of acutetubular necrosis is usually affiliated with liver failure. Some patients mayeven experience the end-stage renal disease.

Tylenol can also cause certain hypersensitivity side effectsand the most common ones include fixed drug eruptions and anaphylaxis but thesetypes of side effects do not occur that frequently. Hematologic side effects ofTylenol include rare cases of acute thrombocytopenia which are usuallyassociated with one’s sensitivity to acetaminophen glucuronide.

Some other rarecases have also included methemoglobinemia as well. Most dermatologic sideeffects of Tylenol are rare but they still do sometimes occur and they includeerythematous skin rashes, purpura fulminans, bullous erythema and epidermalnecrolysis. Respiratory side effects are not that common for Tylenol, but stillthere are some cases of eosinophillic pneumonia that have been reported.Cardiovascular side effects of Tylenol most commonly include a significantdecrease in blood pressure and sometimes even hypotension may occur. It shouldbe stressed that no cardiovascular side effects are associated with thesymptoms of anaphylaxis. Metabolic side effects of Tylenol includes metabolicacidosis but it is usually caused by a massive overdose.

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