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Dydrogesterone is synthetic hormone progesterone. The brand name is Duphaston. It is used for regulating menstrual cycle. This medication is non-oestrogenic, non-androgenic, non-anabolic, non-corticoid. Dydrogesterone acts directly on the uterus without contraceptive effect.

Many menstrual disorders result from lack of progesterone in the body. Also, progesterone effects development of strong uterus lining (endometrium) vital for pregnancy. Low progesterone level occurs when fertilized egg does not attach to the womb lining by the end of menstrual cycle. This leads to menstruation. High level or hormone progesterone is essential for maintaining pregnancy.

Dydrogesterone can be recommended in treatment of infertility, premenstrual syndrome, endometriosis and irregular or painful menstruations. Dydrogesterone is used in hormone replacement therapy. This medication can also help in preventing miscarriage or recurrence of miscarriage.

Dydrogesterone is activated through oral consumption. Depending on the treated disorder, Dydrogestrone is taken on certain days during menstrual cycle in recommended doses.

IndicationsDydrogesterone is used for:

Threatened and habitual abortion. Dydrogesteroone decreases the incidence of first trimester abortions and relaxes the smooth musculature of the uterus. Dysmenorrhea. Dydrogesterone relieves the pain associated to menstrual periods. Absence of menstruation due to oestrogen therapy. Dydrogesterone can be used to minimize the overgrowth of endometrial lining. Irregular menstrual cycles. Dydrogesterone successfully regulates menstrual cycle. Premenstrual syndrome (PMS). Dydrogesterone alleviates the symptoms related to premenstrual syndrome. Infertility. Women who are taking Dydrogesterone increase the chance of getting pregnant by almost 50%. This is due to this medicine’s capability to alleviate luteal insufficiency. Infertility caused by a luteal insufficiency. Endometrosis. It is a condition of excess growth in the tissues in the endometrial lining. Hormonal replacement therapy. Dydrogesterone can prevent hot flushes in menopausal women. This medication can also prevent long-term effects of the menopause such as bone resorption and changes in blood lipids. Duphaston is safe during pregnancy and may be prescribed to women who are at risk of having a miscarriage or who have suffered repeated miscarriages proven to be related to a progesterone insufficiency.

Side Effects of DydrogesteroneDydregesterone is safe and well-tolerated. The incidence of side effects is remarkably low.

Possible side effects of Dydrogesterone may include following: gastrointestinal disturbances, allergic skin rashes, changes in libido, acne, breast tenderness, fluid retention, dizziness, headache, nausea, mental depression, and menstrual spotting between periods.

These side affects do not necessarily occur in everyone but they are associated with Dydrogesterone. Use cautiously when pregnant and while breastfeeding.

Do not use Dydrogesterone if you are allergic to this medication or any of its components.

Contraindications include: hypersensitivity, pregnancy, undiagnosed abnormal vaginal bleeding, cerebrovascular or coronary artery disease, carcinoma of the breast or genital organs and hepatic dysfunction.

As it was mentioned above, Dydrogesterone is taken orally. The duration and frequency of treatment must be established by qualified medical worker.

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