Creatinine is an amino acid normally found in the human organism. This substance has been proved to be responsible for our strength, youthful appearance and agility. Our own activity determines how much creatinine the body will produce, because the muscle activity creates this substance as the waste product of metabolism.
Creatinine is therefore transported through the blood, filtered by the kidneys and then disposed through urine in small amounts. Kidneys are the organ responsible for the maintenance of normal creatinine level, so when there is a more creatinine in the blood than it should be – something is wrong with the kidneys. So, one way to diagnose the function of the kidneys is to measure the amount of creatinine in the blood, during standard blood tests. People that have been diagnosed with extremely high creatinine in the blood are suspected to experience kidney failure.
Creatinine can be checked using creatinine clearance test. This test is found useful to estimate the function of patients’ kidneys and the doctor will determine the level of creatinine in the blood and in the urine over 24 hours. Other tests might include examination of urine for biological and chemical content, X-rays and scans. This further testing will enable the doctors to determine exact cause of heightened creatinine in the blood.
How Much Creatinine is Normal
In order to assess the amount of creatinine in the blood one must know the normal blood level of creatinine. Adult males usually have some 0.6 to 1.2mg/dl (milligrams per deciliter) of creatinine in the blood. Adult females are normally found to have slightly lower creatinine level – about 0.5 and 1.1mg/dl, and teenagers have almost the same amount as women – 0.5 to 1.0mg/dl.
People having just one kidney will have about 1.8 to 1.9mg/dl of creatinine in the blood.
Babies, children and teenagers’ creatinine level depends on the development of their muscles. Infants are expected to have around 1.2 to 1.2mg/dl of creatinine, and children about 0.3 to 0.7mg/dl.
Who Can Experience Heightened Creatinine?
People with prominent muscles will normally have more creatinine in their blood. So, it is perfectly normal that men especially those young and fit, or athletes of both sexes will have higher level of creatinine in the blood. Babies or elderly don’t have so much muscles and their creatinine level is expected to be lower.
When someone is experiencing kidney problem that person will usually also have a high level of blood creatinine. Since creatinine is filtered through the kidneys, if there is something wrong with these organs it will certainly reflect on the level of all substances going through them, including creatinine.
Different diseases and conditions are known to affect the filtration ability of the kidneys, including hypertension and diabetes mellitus.