What exactly is allopurinol and why do people use it?
One of the medications that are officially approved for thetreatment of various health issues provoked by increased levels of the uricacid is allopurinol. Some of these health issues are gout, increased uric acid levels,which are result of cancer treatment, and kidney stones in cases of those whohave high levels of uric acid. When it comes to the way in which it works, the entiremechanism of action consists of simply inhibiting a particular enzyme that is responsiblefor production of this acid in the human organism, which further affects therate at which the uric acid is produced.
Risks and side effects associated with allopurinol
First of all, it should be noted that this medication can beused in cases of children who have cancer and increased levels of uric acid. Thisdoes not mean that its use is safe for everyone or that it is side effect free,but it is definitely tolerated well by the majority of those who use it. As forthe side effects, they can be prevented in some cases, or the possibility thatthey will occur can be minimized, but unfortunately, that is not possible always.For example, people who suffer from liver cirrhosis, liver failure, or some otherdisease of this organ, as well as people who suffer from certain kidney diseasesor allergies of any kind, should inform their doctor in time, because thismedication can cause additional problems in such cases. As for women who areeither pregnant or breastfeeding, they should also warn their doctor about thisdetail, because the use of allopurinol is not considered safe during pregnancy,and due to its ability to pass through the breast milk, its use should bediscussed in cases of breastfeeding mothers as well.
When it comes to the possible interaction, the list ofmedications that allopurinol should not be combined with is rater long, but ACEinhibitors, antacids, diuretics are a part of that list as well. In case problems such as painful urination, easy bruising, easy bleeding, or irritation of the eyes occur, it is necessaryto consult a doctor. The same goes for signs that indicate some problems withliver (including even the loss of appetite and weight), frequent infections,skin rash or some other sign of allergic reaction, while other side effects are notso serious and they do not require medical attention unless they are persistent.