Couldn't find what you looking for?

TRY OUR SEARCH!

Hand dermatitis or hand eczema is dermatitis affecting the hands. It can be of different types and associated with different underlying causes. For instance, hand dermatitis can be the essence of contact dermatitis, seborrheic dermatitis or dyshidrotic dermatitis. Some people develop dermatitis of the hands due to exposure to certain chemicals at their work. They are known to suffer from so-called occupational dermatitis.

Hand dermatitis is in fact most commonly reported in people who expose their hands excessively to harsh substances without adequate protection. This is the reason why such dermatitis is frequently reported in people working in industries involving cleaning catering, metalwork, hairdressing, healthcare etc.

The condition may be mild, moderate or severe affecting only the back of the hands or palms as well. The affected skin is red (inflamed), sometimes covered with itchy or non-itchy papules or fluid-filled blisters. There may also be scaling, cracking, weeping and edema.

Hand Eczema and Constitutional Factors

It is confirmed that some individuals are more susceptible to hand dermatitis. They usually have a positive family history of some type of dermatitis like atopic dermatitis or some of the family members are suffering from asthma and hay fever.

Furthermore, people who are stress-prone are also affected more compared to the rest of the population.

Hand Eczema and Irritants

People who frequently immerse their hands in water are at higher risk of developing hand dermatitis. The risk becomes even higher if the water contains detergents or solvents. Such chemicals easily remove the natural protective layer of the skin, making it susceptible to inflammation. Additionally, friction together with repetitive injuries may contribute to hand dermatitis.

Hand Eczema and Allergies

Some people are allergic to certain allergens and develop abnormal immunologic reactions as soon as they get in contact with the causative agent. An example of an allergic reaction affecting the hands is an allergy to latex, a substance used in manufacturing gloves. The allergic reaction usually stays localized and on rather rare occasions may progress into a severe and life-threatening reaction called anaphylaxis.

In order to estimate what allergen a patient is allergic to, doctors usually perform a patch test.

Hand Eczema Treatment Options

Hand eczema can be treated and all patients start to recover soon after the treatment is initiated. In people suffering from severe occupational dermatitis, a change of occupation is a must. In others with mild to moderate inflammation, skin inflammation may be avoided if the person stays away from irritants. Protection of the hands is also important in the prevention of disease recurrence. The hands are supposed to be covered with emollients which serve as highly efficient protectors.

Patients may be sometimes prescribed topical steroids or if there are bacterial infections even topical or oral antibiotics. Dermatitis that lasts for several weeks or is quite severe requires a more complex approach.

Chronic hand eczema (CHE) is a common and burdensome inflammatory skin condition seen in up to 10% of the population, more often in high-risk occupational workers. Topical therapeutics comprise the standard of care, but up to 65% of cases do not resolve after treatment, and moderate-to-severe cases are often resistant to topical therapeutics and require systemic options instead.
  • Most cases of hand eczema are caused by a combination of etiologies. There are three main etiologic classifications of hand eczema: irritant contact dermatitis (ICD), allergic contact dermatitis (ACD), and atopic hand eczema, which accounts for over 50% of cases.
  • Topical steroids – particularly higher potency steroids such as clobetasol propionate – have long demonstrated efficacy, particularly for mild-to-moderate cases, but are associated with adverse effects. The adverse effects associated with topical steroids, including skin atrophy and tachyphylaxis, hinder longer term use, which is often required for the treatment of CHE.
  • Non-steroidal topical treatments such as calcineurin inhibitors and calcipotriol have also shown limited efficacy, but current treatment regimens are not standardized.
  • Positive data for moderate-to-severe CHE has been shown outside of the US through the utilization of alitretinoin, which is a relatively cost-effective systemic drug that has shown efficacy in treating refractory, chronic moderate-to-severe cases of hand eczema. However, it has safety concerns, particularly for women of childbearing age who must adhere to strict birth control measures.
✓ Fact confirmed: Drugs for the Treatment of Chronic Hand Eczema: Successes and Key Challenges Celina Dubin, Ester Del Duca, and Emma Guttman-Yassky; 2020 Dec 31.

Your thoughts on this

User avatar Guest
Captcha