Folic acid is one of the vitamin B. The body requires Folic Acid for the creation of red blood cells and other new cells. There is no folic acid in the food, but there are folates, which have several different types and they are absorbed from food in different amounts. Usually, only one-half to two thirds of folates from food can absorb.
If you buy supplements of folic acid in pharmacies on by own without a prescription prescribed need to know some facts. If folic acid supplements are used in small doses, generally do not show any adverse effects. These supplements, which may occur in the form of capsules, beside folic acid, usually contain some vitamins (B6, B12, Omega-3 acids, phytosterols). Their interaction, in extremely rare cases can cause very serious consequences. If they occur, you must immediately seek medical help. Some of the possible side effects that may occur are:allergic reaction (swelling of the face, lips, tongue, tightness in the chest, difficulty with breathing, rash, hives);skin irritation and numbness and swelling of the entire body;diarrhea, drowsiness;problems with coordination of arm and leg and a sense of stupor in the fingers;itching and burning sensation;swelling, redness or pain at the injection spot;If folic acid is given in the form of professional treatment administrated by a doctor, according to the prescribed doses, cause some adverse effects on body systems.
Folic acid in dose of 15mg/dan in the system of the digestive tract can cause nausea, bloating, anorexia, bitter taste and flatulence.
Negative effects of folic acid on the nervous system can manifest as confusion, poor concentration, insomnia, irritability, depression, anxiety and disturbances in reasoning. One unofficial study confirmed that folic acid therapy may lead to an increase in the number of epileptic attacks. Dose of folic acid of 100mg/dan can create the illusion of entering of severe anemia to hematological remission state, while the nervous symptoms still thrive.
Metabolic adverse effects are related to disturbances in gastrointestinal absorption of zinc. Fall of zinc plasma can be measured in doses of folic acid greater than 400mg/dan. Zinc is essential for the synthesis of proteins, DNA and RNA. Its deficiency is rare but can occur in pregnancy, with intestinal disease, liver cirrhosis, malabsorption, and consuming large amounts of alcohol. This deficiency is usually manifested through the fall of immunities, loss of taste, skin problems in the area of face, limbs, skin folds and perineum, hair loss, irritability and depression, and diarrhea.
Hipersensitivity of folic acid is found in very rare cases and manifested as rash, itch, dyspnoea with bronchospasm and discomfort. It was even reported one case of anaphylaxis.