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Zuclopenthixol (Zuclopentixol,Cisordinol, Clopixol,Acuphase) is an antipsychotic drug used to treat psychotic episodes,especially schizophrenia.

The medication is blocking many receptors in the brain,including dopamine receptors, which controls behavior and mood. Schizophreniaand other psychotic illnesses are caused by the excessive dopamine activity inthe brain. Blocking the dopamine receptors the drug is controlling psychotic illnesses,calming the patients and easing aggression and hallucinations.

Possible side effects of zuclopenthixol are tremor andrigidity of hands, legs or face. Sometimes, patients experienceanxiety, agitation and drowsiness.

The medication could induce a serious condition known as tardivedyskinesia, with the rhythmical movements of the whole face or parts of theface (tongue, mouth and jaw) and sometimes unconscious moves of the arms andlegs.

Neuroleptic malignant syndrome is a rare and severe sideeffect. High temperature, pale face, sweating and a fast heartbeat are thesymptoms of this condition, and if it happens the drug should be stopped instantly.

Oculogyric crisis is another serious side effect, whichseeks immediate medical attention. The condition is presented with uncontrolledrolling of the eyes and neck.

Zuclopenthixol affects the heart, increasing heart beat andheart rate and causing low blood pressure.

The drug is showing effects to the nervous system. Patients arecomplaining about headaches, insomnia or nightmares, and memory and speech problems.

Older patients have problem with the body temperature and abnormalsweating. Their body is reflecting the temperature of the outside, so theycould easily suffer form the heat stroke during summer and hypothermia duringcold weather.

Gastrointestinal side effects include nausea, vomiting, constipation,indigestion. Problems with urine are not rare, along with increasedsalivation or dry mouth. Patients report weight and appetite changes and sexualproblems.

Other reported side effects include: eye problems, skinreactions, seizures, hyperprolactinaemia (high levels of milk producing hormone,prolactin), blood related problems (most likely problems with white blood cells), andpossible liver problems.

Make sure to inform your doctor about every other medicationor remedy you have been using, for zuclopenthixol treatment may interfere withthem and lead to some serious side effects.

It is important not to drive or operate any machinery whileon zuclopenthixol therapy, because the drug may cause vision problems and sleepiness.

Alcohol should be avoided for it could enhance sleepiness.

Any abnormal movements of the face should be reported to thedoctor immediately, to check for possible tardive dyskinesia.

Inform you doctor about high fever, excessive sweating,drowsiness and stiff muscles, because these symptoms may indicate neurolepticmalignant syndrome.

The medication should be used as doctor prescribed it. Do notstop taking the drug even if you are feeling better, because the symptoms willcome back. The doctor will decide if and how to stop the use of zuclopenthixol.

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